Longevity Clinics: What They Do, What They Cost and What to Ask

A longevity clinic is a private practice that runs extensive tests, such as advanced imaging, VO2 max, blood panels and "biological age" clocks, then builds a personal plan to help you stay healthy longer. Memberships often cost tens of thousands of dollars a year. Some of what they offer rests on solid evidence. Some of it doesn't.

Longevity clinics have gone from a Silicon Valley niche to storefronts in most big cities. The pitch is appealing: find problems early, measure how fast you're aging and fix it. This guide covers what these clinics actually do, what they charge, which parts the evidence backs, which parts regulators have warned about and the questions to ask before you pay.

Last reviewed: October 25, 2026.

Key Takeaways

• There's no standard model for a longevity clinic. Services range from a doctor-led physical with fitness testing to luxury spa weeks and experimental infusions.
• A 2025 review in Aging found annual memberships often run €10,000 to €50,000, with some packages above €100,000.
• The best-supported parts are the basics: fitness testing, strength and body composition, standard blood work and help changing exercise, diet and sleep habits.
• The FDA has warned that unapproved stem cell and exosome products sold outside a clinical trial are likely illegal, and that it knows of no evidence young-donor plasma helps with aging.
• Biological age tests are still debated as clinical tools. Treat a "biological age" score as one data point, not a verdict.

What does a longevity clinic do?

Most longevity clinics follow the same pattern: a big round of testing up front, a personalized plan, then follow-up visits and repeat testing. A 2025 commentary in the journal Aging by Marco Demaria, a researcher at the European Research Institute for the Biology of Ageing, lists what a typical client may go through: genome sequencing, "multi-omics" profiling, advanced imaging and full-body scans, immune and microbiome tests and epigenetic testing. The plans that follow can include exercise prescriptions, nutrition advice, supplements, sleep and stress coaching, hormone replacement or more experimental options such as stem cell infusions, peptide injections and plasma exchange (Demaria, 2025).

Some clinics are run inside academic medical centers. Northwestern Medicine's Human Longevity Clinic, for example, lists VO2 max testing, epigenetic clocks, an AI-based retinal age test, a PAI-1 blood test, a physical function assessment, a DXA body composition scan and pulse wave velocity (a measure of artery stiffness), followed by a personalized plan (Northwestern Medicine).

Others are closer to luxury retreats, with week-long stays that mix diagnostics, diet programs and spa therapies. A 2024 review put it plainly: there is currently no universally accepted standard model for longevity clinics (Mironov et al., 2024).

How much does a longevity clinic cost?

A lot. The Demaria review collected published prices for well-known clinics. Here's what it reported. Prices are the review's figures, many are "from" rates, and they change, so check with any clinic directly.

Source: Table 1 in Demaria, 2025. The review notes that many clinics frame themselves as "wellness" providers rather than medical ones, which matters for oversight. Don't assume insurance will pay. Ask the clinic what, if anything, it bills to insurance, and check with your plan.

Is longevity medicine legit?

Parts of it are. The idea behind it, measuring health early and acting before problems show up, is sound, and Demaria credits clinics with two real strengths: they follow people for years, which could produce useful long-term data, and they get clients engaged in their own health. He also notes that lifestyle changes remain the most robust interventions for healthy aging.

The same review lists the weak spots:

• Unproven add-ons. Supplements and IV drips sold with little validation, and stem cell or experimental biologic infusions offered without solid safety data.
• Over-sold test results. Biological age scores from epigenetic or telomere tests are presented as definitive, even though their precision and clinical usefulness are still debated.
• Little connection to research. Most clinics don't work with academic aging researchers or geriatricians, so their results are rarely validated or published.
• A regulatory grey zone. Calling themselves wellness providers can let clinics avoid the oversight a hospital would face.

Demaria warns that claims like "reversing aging" or "guaranteeing 20 extra years of life" may attract customers but will "surely underdeliver." If a clinic leads with promises like that, take note.

Which longevity clinic tests are worth it?

Here's how the common offerings line up against what the evidence and regulators say.

Biological age tests

Epigenetic clocks estimate "biological age" from patterns of DNA methylation. A 2026 review in GeroScience from researchers at Mount Sinai said these measures may become useful for tracking personalized longevity plans, but that implementing them in clinical practice has been challenging, and race, sex and chronological age all affect how well they predict (Tuminello et al., 2026). Our guide to biological age tests explains the main types and their limits.

Full-body scans

The FDA's consumer page on whole-body CT screening says the agency knows of no scientific evidence that scanning people without symptoms provides more benefit than harm, and that medical professional societies haven't endorsed it. CT exposes you to radiation, which may carry a very small increase in lifetime cancer risk, and "false" leads can prompt more, unnecessary testing. The FDA's advice is to weigh the risks and benefits with your physician first (FDA). That page is about CT. Whole-body MRI doesn't use X-rays, but the same question of false alarms and follow-up testing is worth asking.

Stem cells, exosomes and young plasma

The FDA says unapproved regenerative medicine products, including stem cells, fat-derived cells, umbilical cord products and exosomes, need FDA oversight in a clinical trial before they can be used. It has received reports of blindness, tumor formation and infections from these products. In the agency's words: "if you are being charged for these products or offered these products outside of a clinical trial, you are likely being deceived and offered a product illegally." It also warns that a listing on clinicaltrials.gov or an FDA registration doesn't mean a product is approved (FDA).

On "young plasma," infusions of plasma from young donors (for example, ages 18 to 30) that some businesses have sold for up to thousands of dollars per infusion, the FDA says it has not approved it for aging or memory loss and isn't aware of evidence that it works for those uses. Plasma infusions also carry risks such as infections and allergic reactions (FDA).

What should you ask a longevity clinic before you pay?

Bring this list to the first call:

• Who's in charge of my care? Ask for the names, licenses and board certifications of the physicians, and whether a doctor or a coach reviews your results.
• What exactly is included, and what costs extra? Get the full price in writing, including repeat testing, supplements and any add-on therapies.
• What's the evidence for each test? Ask what decision each result will change. If a test won't change anything you do, you may not need it.
• How do you handle incidental findings? Ask who follows up on an unexpected scan result and what further testing usually costs.
• Is any therapy part of a clinical trial? For stem cells, exosomes or plasma, ask whether it's under FDA oversight in a clinical trial. Remember the FDA's point that a clinicaltrials.gov listing alone doesn't mean approval.
• Will my own doctor get the results? A good clinic works with your primary care doctor, not around them.
• Do you sell supplements? If so, ask for the full label for anything recommended. Our guide on how to read a Supplement Facts label shows what to check.
• Who owns my data? Genetic and health data are sensitive. Ask how they're stored, shared and deleted.

Can you get most of the benefit without a clinic?

Much of it, yes. The interventions Demaria calls the most robust, exercise, diet and other lifestyle habits, don't need a membership. A practical do-it-yourself version looks like this:

• A yearly checkup with your own doctor, including the standard screenings and blood work recommended for your age.
• Regular aerobic exercise and strength training two or more days a week, as covered in our exercise and longevity guide.
• A mostly whole-food diet; see nutrition for healthy aging.
• Simple tracking you can repeat, such as resting heart rate, a timed walk, how many times you can stand up from a chair in 30 seconds or your weight and waist size.

Our healthspan vs lifespan guide explains why these basics matter. If you're weighing supplements as part of a longevity plan, our longevity supplements buyer's guide covers what the research does and doesn't show.

Frequently asked questions

Is longevity medicine real?

Partly. Testing fitness, strength and standard blood markers and acting on them is mainstream medicine. But there's no standard model for longevity clinics, and some sell services the FDA hasn't approved, such as stem cell and young plasma infusions.

What does a longevity physician do?

A longevity physician focuses on keeping healthy people healthy longer. That usually means extensive testing, then a personal plan built around exercise, nutrition, sleep and sometimes medication or supplements, with repeat testing to track progress.

How much does a longevity clinic cost?

A 2025 review found memberships often run €10,000 to €50,000 a year, with some packages above €100,000. Listed U.S. examples ranged from about $8,000 to $85,000 a year.

Does insurance cover longevity clinics?

Don't assume it does. Ask the clinic what it bills to insurance and check with your plan. Some standard tests may be covered when your own doctor orders them.

Are full-body scans worth it?

The FDA says it knows of no evidence that whole-body CT scanning of people without symptoms does more good than harm, and professional societies haven't endorsed it. Talk it over with your doctor first.

How do I find a good longevity clinic near me?

Start with academic medical centers, some of which now run longevity clinics, and use the questions above. Be cautious of any clinic that promises to reverse aging or sells stem cells or young plasma outside a clinical trial.

Sources

• Demaria M. Longevity clinics: between promise and peril. Aging (Albany NY). 2025.
• Mironov S, Borysova O, Morgunov I, Zhou Z, Moskalev A. A Framework for an Effective Healthy Longevity Clinic. Aging Dis. 2024.
• Tuminello S, Anika R, Turner W, et al. Integrating biological aging into clinical practice: a review and path forward for precision longevity medicine. GeroScience. 2026.
• U.S. Food and Drug Administration. Important Patient and Consumer Information About Regenerative Medicine Therapies.
• U.S. Food and Drug Administration. Update to Important Information about Young Donor Plasma Infusions Offered for Profit. 2024.
• U.S. Food and Drug Administration. Full-Body CT Scans: What You Need to Know.
• Northwestern Medicine. Human Longevity Clinic.

Disclosure: OPA Nutrition sells supplements, including products mentioned in this article. This content is for education only and is not medical advice. Statements about dietary supplements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Talk to your healthcare provider before using any supplement, especially if you take medication or have a medical condition.